Natural Sciences · Advanced · Lesson 4 of 7
Getting In
Lipinski’s rule of five
An interactive lesson with 5 steps, about 5 minutes: you predict, drag and solve, with instant feedback on every answer. It runs in your browser and needs JavaScript.
What you’ll learn
- Lipinski: MW < 500, logP < 5, ≤ 5 donors, ≤ 10 acceptors.
- Neutral forms cross membranes; pH sets how much is neutral.
Steps
- The rule of five
- Count the donors
- Rule breakers
- Aspirin in the stomach
- Brain drugs