Dose–Response

Potency and efficacy

An interactive lesson with 4 steps, about 5 minutes: you predict, drag and solve, with instant feedback on every answer. It runs in your browser and needs JavaScript.

What you’ll learn

• Dose–response on a log scale is S-shaped.
• Potency = EC₅₀ (lower is more potent); efficacy = maximum effect.
• Therapeutic index = TD₅₀ / ED₅₀.

Steps

1. An S-shaped curve
2. Most potent
3. Read the EC₅₀
4. The safety margin